ABSTRACT
Yon
Hee Shim, M.D., Chul Ho Chang, M.D., Jong Seok Lee, M.D., Seung Jung Kim, M.D.,
and Cheung Soo Shin, M.D.
Background:
Hyperglycemia
is common in critically ill patients, even in those without diabetes, and it is
known to increase mortality in patients with or without diabetes in the
settings of acute myocardial infarction or acute stroke. However, the clinical effects
of admission hyperglycemia are uncertain, and no data is available that
compares the prognosis in a heterogenous group of critically ill patients. The
aim of this study was to evaluate the effect of hyperglycemia on prognosis in a
heterogenous group of critically ill patients with or without diabetes.
Methods:
The
medical records of 858 consecutive adult patients admitted to a general
intensive care unit (ICU) at a University Hospital over 21 months were
reviewed. Patients with no records of blood glucose measurements and patients
with normoglycemia during the first 3 days were excluded. The remaining 349
patients with hyperglycemia were divided into two groups according to a
previous history of diabetes. Hyperglycemia was defined as a fasting blood
glucose level of 140 mg/dl or more, or a random blood glucose level of 200
mg/dl or more on 2 or more determinations. The primary end-point of the study
was ICU and in-hospital mortality, and its secondary end-point included length
of stay in the ICU and hospital.
Results:
There
were no significant differences in ICU mortality (17.6/19.0%), in-hospital
mortality (24.5/24.3%), ICU length of stay (6.6 ± 11.9/6.6 ± 10.4 days),
and hospital length of stay (11.4 ± 29.0/12.8 ± 24.3 days)
between diabetics and nondiabetics.
Conclusions:
Our
results indicate that the effects of hyperglycemia on the prognosis of critically ill patients do not
differ diabetics from nondiabetics. (Korean Journal Anesthesiol 2004; 47: S
10-S 13)
Full Text: CLICK HERE
No comments:
Post a Comment